How do states’ positions across multiple and interconnected economic networks affect their power? The Weaponized Interdependence (WI) scholarship emphasizes that states centrally located in global economic networks have access to new sources of coercion. In this paper, we look at how their positions across multiple networks interact with each other to create new opportunities and vulnerabilities. We use network analysis to map the semiconductor supply chain and show that it can be viewed as four interrelated networks: (1) design, (2) raw material, (3) manufacturing equipment, and (4) assembled chips. We then highlight how states’ centrality varies across these networks and how it shapes their respective opportunities for coercion. Looking specifically at the United States, we emphasize how its centrality in the design network enables it to weaponize chokepoints in the trade network of assembled chips. In so doing the paper makes three contributions. First, it highlights how interactions among multiple economic networks provide new opportunities for states to weaponize interdependence. Second, it contributes to recent attempts using network analysis to analyze structural power on the global stage. Last, it demonstrates how network methodology can help detect potential (ab)uses of WI and how the potential for weaponization evolves over time.